a real bitch
A real bitch doesn't let people walk all over her. She'll fight back if you try to mess with her.
You called her a 'total mess.' She said, 'You're a total mess, and I'm not even mad.'
Your friend tried to make fun of her. She just stood up and said, 'You're a total waste of oxygen.'
You said she was a 'weak link.' She said, 'You're the weak link.'