Jacking up
When a person or loser is stuck getting high off of heroin, a terrible drug, and it’s like stabbing their veins with a rusty knife
That guy is jacked up on heroin and looks like he got stabbed by a rusty spoon.
She’s jacked up on heroin and her veins look like they’re about to burst.
He got jacked up on heroin and now he looks like a melted crayon.