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The ultimate insult you throw at someone you used to like. It means you're so stunned by their betrayal that you're ready to cry, yell, and maybe even throw a pizza at them.
I thought we were friends. Now I'm gonna throw my pizza at your face.
You said you'd never leave me. I thought we were friends. Now I'm gonna leave you.
I thought we were friends. You just called me a f***ing loser in front of everyone.