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G2U is a way to call a girl with huge, massive, or extra big boobs. It's like saying her chest is so big it could take a hit from a wrecking ball and not flinch.
My cousin got called G2U because she wore a bra that looked like it belonged to a cow.
At the mall, some guy yelled G2U at my sister because she was eating a giant ice cream cone.
My teacher said I was G2U because I had a backpack that looked like it had a whole family in it.