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D2M means you're doing too much, and it's usually because you're high, drunk, or just plain stupid. You're like a maniac with no brakes.
Bro, I D2M'd my entire weekend. I partied, smoked, and even tried to rap at a bar. I was a mess.
I D2M'd my dog. I gave him three different types of treats, and he still hated me.
I D2M'd my math test. I answered every question with a swear word and got a zero.