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A Goner is a person who has given up completely and is too tired to even care if they live or die.
My dog is a goner. He won't eat. He won't play. He just stares at the wall like he's waiting for the end of the world.
My math teacher is a goner. He failed 10 kids today and didn't even flinch.
My cousin is a goner. He took one look at the chicken and ran out of the restaurant.