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A tiny annoyance that turns a good day into a disaster because you're too lazy to deal with it.
My mom's new cat is a fly in the ointment. I was about to eat my cereal in peace, and it decided to claw my face.
My friend's new haircut is a fly in the ointment. I thought he looked cool, now he looks like a chia pet.
My brother's loud snoring is a fly in the ointment. I was about to fall asleep, and he turned it into a symphony.